It is not intended as a substitute for professional medical advice, diagnosis or treatment. Crestor is the brand name for rosuvastatin, a prescription drug used to treat high cholesterol levels crestor is in a class of drugs known as statins, which slow the buildup of plaque in your. Aug 28, 2009 antiinflammatory effects of rosuvastatin recent data have show multiple mechanisms for statins in reducing the risk of cardiovascular diseases. All of these side effects of crestor are rare, but they should be mentioned. Antacids reduce the absorption of rosuvastatin and should be administered two hours after rosuvastatin. Crestor is available in tablets of 5, 10, 20 and 40 mg strengths. Rhabdomyolysis is a rare form of muscle damage that can lead to severe kidney injury or failure. The content of this database of side effects adverse drug reactions is intended for educational and scientific research purposes only. Rosuvastatin complete drug information, side effects and. Ezetimibe is a newly developed lipidlowering drug that can inhibit. Dosage and administration, hefh in pediatric patients 10 to 17 years of age 2. Rosuvastatin is an inexpensive drug used to lower cholesterol levels. Youre more likely to have side effects if youre a female, are 65 years or older, drink alcohol every day, or take more than one medicine for cholesterol. Call your doctor for medical advice about side effects.
Rosuvastatin is used to lower cholesterol and triglycerides types of fat in the blood. Although not all of these side effects may occur, if. Effects of rosuvastatin and atorvastatin on renal function metaanalysis article pdf available in circulation journal 765. Take rosuvastatin at around the same time every day. These interactions can cause your body to metabolize the medicines differently than intended, increase the risk of muscle problems, and cause significant reactions, among other things. The safety of aggressive statin therapy mayo clinic proceedings. Dec, 2011 a recent study published by the new england journal of medicine pitted two of the top statins against each other to see which is more effective atorvastatin lipitor or rosuvastatin crestor. Drug interactions are reported among people who take metoprolol tartrate and rosuvastatin calcium together. Rosuvastatin is used in adults and children who are at least 10 years old. Rosuvastatin is used for decrease the amount of bad cholesterol lowdensity lipoprotein ldl, triglycerides in the blood, increase the amount of good cholesterol highdensity lipoprotein hdl in the blood, decrease the amount of cholesterol, fats, and other fatty substances in the blood in children and adolescents of age 10 to 17 years, or treat a genetic condition characterized by. Crestor side effects rosuvastatin by duane graveline, m. Rosuvastatin can cause side effects in some people. Why isnt rosuvastatin prescribed more frequently than. A recent study published by the new england journal of medicine pitted two of the top statins against each other to see which is more effective atorvastatin lipitor or rosuvastatin crestor.
Atorvastatin a and rosuvastatin r are highly effective and widely used statins. Advise patients to promptly report unexplained muscle pain, tenderness, or weakness and discontinue crestor if signs or symptoms. Reducing side effects if you do have side effects, you can take steps to help relieve them or even make them go away. In canada call your doctor for medical advice about side effects. Call your health care professional right away if you experience unexplained muscle pain, tenderness, or weakness especially with fever. Pain, burning sensation, hypersensitivity, sleep disorder, oedema. Some will disappear in days or less, some could last much longer. Rosuvastatin uses, side effects, substitutes, composition. Efficacy and safety of rosuvastatin and atorvastatin. In turn, they help lower cholesterol, reduce risk for cardiac events and. Treatmentrelated adverse effects in the rosuvastatin plus fenofibrate groups were.
Jan 12, 2017 our rosuvastatin calcium side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Side effects of crestor rosuvastatin calcium, warnings, uses. Our crestor side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Rosuvastatin belongs to the group of medications known as hmg coa reductase inhibitors statins. Rosuvastatin is used for decrease the amount of bad cholesterol lowdensity lipoprotein ldl, triglycerides in the blood, increase the amount of good cholesterol highdensity lipoprotein hdl in the blood, decrease the amount of cholesterol, fats, and other fatty substances in the blood in children and adolescents of age 10 to 17 years, or treat a genetic condition. Atorvastatin reduced ldlc the most at a dose of 40 mg 22.
Crestor side effects rhabdomyolysis, diabetes, liver injury. What are the side effects of the cholesterol drug crestor. Rosuvastatin calcium side effects by likelihood and severity common side effects. It is usually taken once a day with or without food. Learn about side effects, warnings, dosage, and more. Food and drug administration approved crestor rosuvastatin for treating cholesterol in 2003. Hypersensitivity to toes, ankle swelling and pitting edema on calves. Our rosuvastatin calcium side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Know rosuvastatin uses, sideeffects, composition, substitutes, drug. In adults, crestor is prescribed along with diet to lower high cholesterol and to slow plaque buildup in arteries as part of a treatment plan to lower cholesterol to goal. Crestor is also used to lower the risk of stroke, heart attack, and other complications in men 50 years and older or women 60 years and older who have coronary heart disease or other risk factors. Abnormal tests usually return to normal even if a statin is continued, but if the.
Crestor rosuvastatin calcium may cause serious side effects, including. The incidence of treatmentrelated adverse effects when combining all fenofibric acid and. Statins is a class of drugs that lowers the level of cholesterol in the blood by. While the drug can be very helpful for some, there are notable side effects that may take place. Rosuvastatin oral crestor side effects, medical uses. In those cases, it is necessary to combine statins with other kinds of lipidlowering drugs. Generic rosuvastatin is covered by most medicare and insurance plans, but some pharmacy coupons or cash prices may be l. Rosuvastatin 10 mg and 20 mg was the most effective at reducing ldlc 29.
Jan 10, 2014 crestor is a statin drug that contains rosuvastatin. For commercial use or customized versions, please contact biobyte solutions gmbh disclaimer. Rosuvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors. Side effects of crestor what are the possible side effects of crestor. Rosuvastatin oral crestor side effects, medical uses, and. Serious side effects may include rhabdomyolysis, liver problems, and diabetes. Antacidspabsorption administer 2 hr after rosuvastatin. Crestor is an hmg coa reductase inhibitor indicated for. Rosuvastatin calcium sleep disorder reports druginformer.
Rosuvastatin may also be used for purposes not listed in this medication guide. Jul 03, 2012 rosuvastatin can cause side effects in some people. Side effects requiring immediate medical attention. This report covers adverse effects of statins, adverse events associated with. Rosuvastatin calcium libido decreased reports druginformer. A few rare side effects seen with this medicine include kidney failure, pancreatitis, and allergic reactions. Along with its needed effects, rosuvastatin may cause some unwanted effects. Except as otherwise noted, this work is licensed under a creative commons attributionnoncommercialshare alike 4. Rosuvastatin, sold under the trade name crestor among others, is a statin medication, used to. It is used, along with a healthy diet and exercise program, to improve cholesterol levels by lowering bad cholesterol and raising good cholesterol. Side effects of rosuvastatin calcium tablets rosuvastatin. Moreover, rosuvastatin 10 mg reduced triglycerides the most.
Side effects, drug interactions, and patient information is also provided. This may be an early sign of a rare muscle problem that could lead to serious kidney problems. Metaregression analysis was performed to determine whether the effects of rosuvastatin therapy were modulated by the prespecified factors. If experienced, these tend to have a severe expression. At the time, the agency knew about cases of rhabdomyolysis during crestors premarketing trials. Rosuvastatin side effects some common side effects of rosuvastatin include headache, muscle aches, dizziness, and nausea. When administered with cyclosporine, the blood level of rosuvastatin increases seven fold, and this could increase the side effects of rosuvastatin rosuvastatin increases the action of the blood thinner warfarin and could increase the risk of bleeding from warfarin. Infrequent but serious side effects of crestor include rhabdomyolysis muscle damage or destruction that can lead to acute renal failure and liver damage.
On this page about rosuvastatin apo you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme pbs as well as other useful information. Dec 14, 2016 all of these side effects of crestor are rare, but they should be mentioned. However, conflicting results have been reported regarding their renal effects. Generic rosuvastatin is covered by most medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. In particular, the hmgcoa reductase inhibitors reduce the incidence of ischemic heart disease, improve endothelial function, reduce left ventricular hypertrophy and adverse remodeling, slow. See below for a comprehensive list of adverse effects. A friend looked up the side effects of all my meds and told me to stop this drug and see what happened. See what the interactions are and for which people. Pain in legs, memory loss, total loss of libido crestor 10mg lowered my total cholesterol from 300 down to 150 and also killed my libido and erections. Rosuvastatin is used for hyperlipidemia, hypertriglyceridemia, type 3 hyperlipoproteinemia etc.
In turn, they help lower cholesterol, reduce risk for. Rationale to use rosuvastatin and fenofibratefenofibric acid combination. Stabbing pain under feet, occasional deep burningpain under balls of feet and heels. Indications, dose, contraindications, sideeffects, interactions, cautions, warnings and other safety information for rosuvastatin. Search results rosuvastatin national library of medicine. Apr 23, 2020 these observations and the known association between statin dose and the risk of side effects suggest that the benefitrisk ratio favors rosuvastatin 40 mg over rosuvastatin 80 mg in this patient.
Prescribing information with patient information pdf 152k you may report side effects related to astrazeneca products by clicking here. The use of rosuvastatin with nicotinic acid, gemfibrozil lopid or other drugs that may cause liver or muscle. Effects of combination of ezetimibe and rosuvastatin on coronary. Drug interactions with rosuvastatin gemfibrozil, ketoconazole, and birth control pills are among the medications that can cause rosuvastatin drug interactions. Crestor rosuvastatin is the most popular drug manufactured by this company, and is actually the fourth top selling drug in the united states. Before taking rosuvastatin, tell your doctor or pharmacist if you are allergic to it. For each study, data regarding final sdldl levels in both the rosuvastatin and atorvastatin groups were used to generate mean differences md and 95 % confidence intervals ci. This is not a complete list of side effects and others may occur.
Caution should be used when prescribing with crestor. Muscle problems, including muscle breakdown, can be serious in some people and rarely cause kidney damage that can lead to death. Rosuvastatin brand name crestor has more spent on it in the u. Statinassociated muscle symptoms sams, the most common statin side effect, are reported by 10% to 25% of patients receiving statin therapy. Rosuvastatin comes as a tablet crestor to take by mouth. Pdf effects of rosuvastatin and atorvastatin on renal. Click on the topics below to find out what patients said about each issue. Crestor is a statin drug that contains rosuvastatin. On this page about rosuvastatin amneal you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme pbs as well as other useful information.
One in 4 americans 40 years of age takes a statin to reduce the risk of myocardial. Crestor rosuvastatin calcium may cause serious side effects, including muscle pain, tenderness and weakness myopathy. Both drugs work in the same way, helping to block a chemical necessary for making cholesterol. Crestor should be taken with water once a day at the same. Monitor inr frequently until stable upon initiation or alteration of crestor therapy. As much as there is scientific evidence to prove that rosuvastatin can reduce high cholesterol, crestor also has many side effects such as causing sleeplessness, joint pain, and severe muscle pain that need to be considered before prolonged usage. The aim of the present study was to compare the effects of a and r on glomerular filtration rate gfr and new onset proteinuria in patients at high cardiovascular risk. Rosuvastatin information, calcium, side effects, dosage. You may report side effects to health canada at 18662342345. In an internet survey of former statin users, 60% reported sams 2 and 62% reported stopping statin therapy because of side effects 2.
Learn about rosuvastatin from patients first hand experiences and trusted online health resources, including dosage, side effects and interactions. If you notice any of the following rare but serious side effects, tell your doctor right away. Crestor rosuvastatin is one of the most effective statins to improve cholesterol. However, people can also combine ezetimibe with either simvastatin or atorvastatin. Side effect duration depends on what the individual side effect is. Find patient medical information for rosuvastatin oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Head to head comparison of efficacy and safety of atorvastatin and. How long do crestor rosuvastatin side effects last. The ncepatp iii ldl cholesterol goals were achieved by 82% to 89% of subjects treated with rosuvastatin 10 to 40 mg compared with 69% to 85% of patients treated with atorvastatin 10 to 80 mg, and drug tolerability was comparable across treatments. Crestor rosuvastatin side effects, dosage, interactions. Rosuvastatin also comes as a capsule ezallor to take by mouth or to open, mix with water, and give through a feeding tube. These statinassociated musculoskeletal side effects can be exacerbated by.